AUTHOR=Zhou Bo , Lan Yueyan , Bi Yifei , Li Chaoxiu , Zhang Xiaohong , Wu Xiaomei TITLE=Relationship Between Occupational Noise and Hypertension in Modern Enterprise Workers: A Case–Control Study JOURNAL=International Journal of Public Health VOLUME=Volume 67 - 2022 YEAR=2022 URL=https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2022.1604997 DOI=10.3389/ijph.2022.1604997 ISSN=1661-8564 ABSTRACT=Objective: The conclusions of the association between occupational noise exposure and hypertension are controversial. Thus we aimed to assess the relationship between occupational noise exposure and hypertension. Methods: This was a case‒control study, a total of 509 cases and 1018 controls from a automobile manufacturing company were included between July and October 2013. Occupational noise exposure was defined as exposure to noise level ≥ 80 dB(A) (Lex,8 h) or CNE ≥ 85 dB(A)-years. To assess the association of noise level, cumulative noise exposure (CNE) and hypertension. Univariate and multi-variate logistic regression were used to calculate the odds ratio (OR) and 95% confidence interval (CI). The restricted cubic splines function model was used to establish the dose response curves. Results: A noise level ≥ 80 dB(A) (Lex,8 h) was significantly associated with hypertension (OR 2.48, 95% CI 1.89–3.24). CNE ≥80 dB(A)-years was significantly associated with hypertension (OR 1.53, 95% CI 1.18–2.00). A nonlinear relationship among noise level, CNE and hypertension was found (P nonlinear<0.05). Conclusions: Our study suggested that occupational noise exposure is a potential risk factor for hy-pertension.