AUTHOR=Lee Chia-Lin , Liu Wei-Ju , Chen Ching-Hsien , Wang Jun-Sing 

TITLE=Associations of Long-Term Physical Activity Trajectories With All-Cause Mortality in a General Population

JOURNAL=International Journal of Public Health

VOLUME=68

YEAR=2023

URL=https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2023.1605332

DOI=10.3389/ijph.2023.1605332

ISSN=1661-8564

ABSTRACT=<p><bold>Objectives:</bold> We investigated the associations of mean levels of leisure-time physical activity (LTPA) and latent LTPA trajectories with all-cause mortality risk.</p><p><bold>Methods:</bold> Trajectories of LTPA were established using group-based trajectory analysis with a latent class growth model in a population-based cohort between 1996 and 2014. A Cox-proportional hazard model was conducted to examine the associations of LTPA quintiles and LTPA trajectories with all-cause mortality.</p><p><bold>Results:</bold> A total of 21,211 participants (age 18–90 years) were analyzed (median follow-up 16.8 years). The study participants were divided into five groups according to percentiles of LTPA (&lt;20th, 20th–&lt;40th, 40th–&lt;60th, 60th–&lt;80th, ≥80th) and LTPA trajectories (low/stable, medium/stable, increasing, decreasing, and fluctuating), respectively. Participants with a decreasing trajectory did not have a significantly lower risk of all-cause mortality despite having the highest baseline level of LTPA. In contrast, participants with a medium/stable (HR 0.84, 95% CI 0.72–0.98, <italic>p</italic> = 0.031) or an increasing (HR 0.57, 95% CI 0.33–0.97, <italic>p</italic> = 0.037) trajectory had a significantly lower risk of all-cause mortality.</p><p><bold>Conclusion:</bold> Promotion of maintaining stable LTPA is beneficial for public health and survival.</p>