AUTHOR=Zhang Yuanyuan , Zhang Yanjun , Ye Ziliang , Yang Sisi , Liu Mengyi , Wu Qimeng , Zhou Chun , He Panpan , Qin Xianhui TITLE=Mobile Phone Use, Genetic Susceptibility and New-Onset Chronic Kidney Diseases JOURNAL=International Journal of Public Health VOLUME=Volume 68 - 2023 YEAR=2023 URL=https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2023.1605358 DOI=10.3389/ijph.2023.1605358 ISSN=1661-8564 ABSTRACT=Objective: To examine the associations of mobile phone use and its use characteristics with new-onset CKD. Methods: 408,743 participants without prior CKD in the UK Biobank were included. The primary outcome was new-onset CKD. Results: During a median follow-up of 12.1 years, 10,797(2.6%) participants occurred CKD. Compared with mobile phone non-users, a significantly higher risk of new-onset CKD was found in mobile phone users (HR=1.07; 95%CI:1.02-1.13). Moreover, among mobile phone users, compared with participants with weekly usage time of mobile phone making or receiving calls <30 mins, a significantly higher risk of new-onset CKD was observed in those with usage time ≥30 mins (HR=1.12; 95%CI:1.07-1.18). Similar results were found using the propensity score matching methods. However, there were no significant associations of length of mobile phone use, and hands-free device/speakerphone use with new-onset CKD among mobile phone users. Conclusions: Mobile phone use was significantly associated with a higher risk of new-onset CKD, especially in those with longer weekly usage time of mobile phones making or receiving calls. Our findings and the underlying mechanisms should be further investigated.