AUTHOR=Hou Xinran , Hu Jiajia , Wang E , Wang Jian , Song Zongbin , Hu Jie , Shi Jian , Zhang Chengliang TITLE=Self-Reported Sleep Disturbance is an Independent Predictor of All-Cause Mortality and Respiratory Disease Mortality in US Adults: A Population-Based Prospective Cohort Study JOURNAL=International Journal of Public Health VOLUME=Volume 68 - 2023 YEAR=2023 URL=https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2023.1605538 DOI=10.3389/ijph.2023.1605538 ISSN=1661-8564 ABSTRACT=Objective: Self-reported sleep disturbance is common but its association with mortality has been rarely investigated. Methods: This prospective cohort analysis included 41257 participants enrolled in the National Health and Nutrition Examination Survey from 2005 to 2018. Self-reported sleep disturbance in the present study referred to the condition of ever consulting doctors or other professionals for trouble sleeping. Univariate and multivariate survey-weighted Cox proportional hazards models were used to evaluate the association of self-reported sleep disturbance with all-cause and disease-specific mortality. Results: Approximately 27.0% of US adults were estimated to have self-reported sleep disturbance. After adjusting for all sociodemographic variables, health behavioral factors, and common comorbidities, participants with self-reported sleep disturbance tend to have higher all-cause mortality risk with a hazard ratio (HR) of 1.17 (95% CI, 1.04-1.32) and chronic lower respiratory disease mortality risk (1.88, 1.26-2.80), but not cardiovascular disease mortality risk (1.19, 0.96-1.46) and cancer mortality risk (1.10, 0.90-1.35). Conclusion: Self-reported sleep disturbance could be associated with higher mortality in adults, and may need to be paid attention to in public health management.