AUTHOR=Chen Hongen , She Yuhang , Dai Shuhong , Wang Li , Tao Na , Huang Shaofen , Xu Shan , Lou Yanmei , Hu Fulan , Li Liping , Wang Changyi 

TITLE=Predicting the Risk of Type 2 Diabetes Mellitus with the New Chinese Diabetes Risk Score in a Cohort Study

JOURNAL=International Journal of Public Health

VOLUME=Volume 68 - 2023

YEAR=2023

URL=https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2023.1605611

DOI=10.3389/ijph.2023.1605611

ISSN=1661-8564

ABSTRACT=Background: Type 2 Diabetes Mellitus (T2DM) has become a serious health problem. The New Chinese Diabetes Risk Score (NCDRS) is a reliable tool to assess T2DM for Chinese population. Our study aimed to evaluate the association between the NCDRS and T2DM risk with a large cohort.
Method: 41,449 participants were enrolled in this cohort study. The NCDRS was calculated and categorized. Hazard Ratios (HRs) and 95% Confidential Intervals (CIs) were made to estimate the association between the baseline NCDRS and the risk of T2DM incidence.
Results: During 141,481.43 person-years of follow-up, 2,050 participants developed T2DM. The adjusted HRs (95%CI) from the lowest to the highest quartile of NCDRS were:1.00, 1.76 (1.25, 2.47), 3.08 (2.25, 4.23), and 4.56 (3.33, 6.24), respectively. T2DM risk was also significantly increased in participants with NCDRS ≥ 25 (HR = 2.12, 95%CI 1.88-2.39) as compared with NCDRS < 25. The restricted cubic spline (RCS) showed a non-linear dose-response association between baseline NCDRS and T2DM risk (Pnonlinearity＜ 0.001).
Conclusion: The NCDRS had a significant positive association with T2DM, the NCDRS is valid in T2DM screening in China.