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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Int. J. Public Health</journal-id>
<journal-title-group>
<journal-title>International Journal of Public Health</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Int. J. Public Health</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">1661-8564</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">1609757</article-id>
<article-id pub-id-type="doi">10.3389/ijph.2026.1609757</article-id>
<article-version article-version-type="Version of Record" vocab="NISO-RP-8-2008"/>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Editorial</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Sleep Disorders: A Blind Spot in Disease Burden Research</article-title>
<alt-title alt-title-type="left-running-head">Welter et al.</alt-title>
<alt-title alt-title-type="right-running-head">Underreported Sleep Disorder Burden</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Welter</surname>
<given-names>Luisa Sophie</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/3425439"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Nissen</surname>
<given-names>Christoph</given-names>
</name>
<xref ref-type="aff" rid="aff3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aff4">
<sup>4</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Rasch</surname>
<given-names>Bj&#xf6;rn</given-names>
</name>
<xref ref-type="aff" rid="aff5">
<sup>5</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Heinzer</surname>
<given-names>Raphael</given-names>
</name>
<xref ref-type="aff" rid="aff6">
<sup>6</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Datta</surname>
<given-names>Alexandre Nikolaus</given-names>
</name>
<xref ref-type="aff" rid="aff7">
<sup>7</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Piovesana</surname>
<given-names>Ester</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bouvier Gallacchi</surname>
<given-names>Martine</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Sterpenich</surname>
<given-names>Virginie</given-names>
</name>
<xref ref-type="aff" rid="aff8">
<sup>8</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bassetti</surname>
<given-names>Claudio Lino Alberto</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aff9">
<sup>9</sup>
</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>1</label>
<institution>European Sleep Foundation</institution>, <city>Lugano</city>, <country country="CH">Switzerland</country>
</aff>
<aff id="aff2">
<label>2</label>
<institution>Swiss Brain Health Foundation</institution>, <city>Riazzino</city>, <country country="CH">Switzerland</country>
</aff>
<aff id="aff3">
<label>3</label>
<institution>Department of Psychiatry, Faculty of Medicine, University of Geneva</institution>, <city>Geneva</city>, <country country="CH">Switzerland</country>
</aff>
<aff id="aff4">
<label>4</label>
<institution>Department of Psychiatry, Geneva University Hospital (HUG)</institution>, <city>Geneva</city>, <country country="CH">Switzerland</country>
</aff>
<aff id="aff5">
<label>5</label>
<institution>Division of Cognitive Biopsychology and Methods, Department of Psychology, University of Fribourg</institution>, <city>Fribourg</city>, <country country="CH">Switzerland</country>
</aff>
<aff id="aff6">
<label>6</label>
<institution>Center for Investigation and Research in Sleep, University Hospital of Lausanne</institution>, <city>Lausanne</city>, <country country="CH">Switzerland</country>
</aff>
<aff id="aff7">
<label>7</label>
<institution>Department of Pediatric Neurology, Developmental Pediatrics and Neurorehabilitation of Northwest Switzerland, University Children&#x2019;s Hospital UKBB Basel and Children&#x2019;s Hospital KSA Aarau</institution>, <city>Basel</city>, <country country="CH">Switzerland</country>
</aff>
<aff id="aff8">
<label>8</label>
<institution>Department of Neuroscience, Faculty of Medicine, University of Geneva</institution>, <city>Geneva</city>, <country country="CH">Switzerland</country>
</aff>
<aff id="aff9">
<label>9</label>
<institution>Medical Faculty, University of Bern and Neurology Department, Inselspital</institution>, <city>Bern</city>, <country country="CH">Switzerland</country>
</aff>
<author-notes>
<corresp id="c001">
<label>&#x2a;</label>Correspondence: Luisa Sophie Welter, <email xlink:href="mailto:luisa-welter@web.de">welter.psy@web.de</email>
</corresp>
</author-notes>
<pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-05-06">
<day>06</day>
<month>05</month>
<year>2026</year>
</pub-date>
<pub-date publication-format="electronic" date-type="collection">
<year>2026</year>
</pub-date>
<volume>71</volume>
<elocation-id>1609757</elocation-id>
<history>
<date date-type="received">
<day>12</day>
<month>03</month>
<year>2026</year>
</date>
<date date-type="rev-recd">
<day>27</day>
<month>03</month>
<year>2026</year>
</date>
<date date-type="accepted">
<day>13</day>
<month>04</month>
<year>2026</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2026 Welter, Nissen, Rasch, Heinzer, Datta, Piovesana, Bouvier Gallacchi, Sterpenich and Bassetti.</copyright-statement>
<copyright-year>2026</copyright-year>
<copyright-holder>Welter, Nissen, Rasch, Heinzer, Datta, Piovesana, Bouvier Gallacchi, Sterpenich and Bassetti</copyright-holder>
<license>
<ali:license_ref start_date="2026-05-06">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
<license-p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</license-p>
</license>
</permissions>
<kwd-group>
<kwd>disability-adjusted life years</kwd>
<kwd>disease burden</kwd>
<kwd>global burden of disease</kwd>
<kwd>public health</kwd>
<kwd>sleep disorders</kwd>
</kwd-group>
<funding-group>
<funding-statement>The author(s) declared that financial support was received for the research and/or publication of this article. The authors&#x2019; listed affiliations covered the publication fee.</funding-statement>
</funding-group>
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<fig-count count="0"/>
<table-count count="0"/>
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<ref-count count="10"/>
<page-count count="2"/>
</counts>
</article-meta>
</front>
<body>
<p>The Global Burden of Disease (GBD) study is a powerful tool for informing public health strategies and policies. Its comprehensive and regularly updated database enables comparisons across health states, regions, and years. However, certain methodological features, combined with the study&#x2019;s considerable influence, may inadvertently contribute to the neglect of conditions that are critical to population health. This Editorial highlights the underrepresentation of sleep disorders in current disease burden research, notably the GBD study.</p>
<p>A substantial body of evidence demonstrates that restorative sleep is essential for mental, physical, and societal wellbeing, as well as economic prosperity [<xref ref-type="bibr" rid="B1">1</xref>]. Sleep health is now recognized as a major determinant of overall health. For instance, recent research drawing on more than 380,000 participants from the UK Biobank indicates that healthy sleep patterns, such as maintaining a sleep duration of 7&#x2013;8&#xa0;h per night, are associated with reduced risks of both overall and site-specific cancers [<xref ref-type="bibr" rid="B2">2</xref>]. Concerningly, sleep disturbances are highly prevalent: approximately 25% of the population reports reduced sleep duration (sleep loss) [<xref ref-type="bibr" rid="B3">3</xref>], and 10% experience excessive daytime sleepiness [<xref ref-type="bibr" rid="B4">4</xref>]. Sleep disorders that reach a clinically significant threshold are also common. For example, severe insomnia affects approximately 8% of the general population [<xref ref-type="bibr" rid="B5">5</xref>], and sleep apnea occurs in 9%&#x2013;38% of adults [<xref ref-type="bibr" rid="B6">6</xref>].</p>
<p>Despite this considerable burden, sleep disorders have been absent from GBD publications since the 2004 update [<xref ref-type="bibr" rid="B7">7</xref>]. They are currently neither included as primary disorders nor as risk factors [<xref ref-type="bibr" rid="B8">8</xref>]. Consequently, key burden metrics such as disability-adjusted life years (DALYs) remain underreported for conditions of inadequate sleep. This gap is notable given that many rare diseases, symptoms, and risk factors are routinely included in GBD analyses. The reason for the exclusion of sleep disorders is unknown to the authors of this Editorial, also considering that GBD estimations could be informed by primary data from large epidemiological resources, such as the UK Biobank [<xref ref-type="bibr" rid="B2">2</xref>].</p>
<p>The exclusion of sleep disorders from multi-disease burden reports such as the GBD study has important implications. As these estimates are widely used to derive prevention and healthcare needs, the exclusion of sleep disorders perpetuates their inadequate management across sectors, including prevention, diagnosis, and treatment. This is particularly concerning because improvements in sleep quality and consistency have beneficial spillover effects on mental, neurological, cardiovascular, and metabolic outcomes as well as on overall health [<xref ref-type="bibr" rid="B1">1</xref>]. Inadequate sleep also poses a direct threat to population health and safety by increasing the risk of traffic accidents [<xref ref-type="bibr" rid="B9">9</xref>]. A recent GBD publication acknowledges that, &#x201c;Psychosocial factors, such as sleep, stress, and social isolation, are increasingly recognized as contributors to neurological conditions and should be quantified in future analyses.&#x201d; [<xref ref-type="bibr" rid="B10">10</xref>]. While we welcome the inclusion of sleep as a determinant of health, we argue that sleep disorders should also be recognized as primary disorders, as reflected in current disease classification systems, including the DSM-5 and ICD-11.</p>
<p>Through this Editorial, we aim to alert policymakers, clinicians, and researchers to the significant gap in burden data on sleep disorders&#x2013;a gap that limits evidence-based prevention and healthcare strategies. Incorporating sleep disorders into burden estimation frameworks, such as the GBD study, would enhance disease recognition and represent a critical step toward improving population health.</p>
</body>
<back>
<sec sec-type="author-contributions" id="s1">
<title>Author Contributions</title>
<p>CB: Data curation. LW, CN, BR, RH, AD, EP, MB, VS, and CB. Project administration: CB, LW. Supervision: CB. Validation: LW, CN, BR, RH, AD, EP, MB, VS, and CB. Writing &#x2013; original draft: LW. Writing &#x2013; review and editing: LW, CN, BR, RH, AD, EP, MB, VS, and CB. All authors contributed to the article and approved the submitted version.</p>
</sec>
<sec sec-type="COI-statement" id="s3">
<title>Conflict of Interest</title>
<p>The authors declare that they do not have any conflicts of interest.</p>
</sec>
<sec sec-type="ai-statement" id="s4">
<title>Generative AI Statement</title>
<p>The author(s) declared that generative AI was used in the creation of this manuscript. Exclusively to improve wording, ChatGPT was used in this article. No artificial intelligence was used for the research and development of ideas presented in this work.</p>
<p>Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible. If you identify any issues, please contact us.</p>
</sec>
<ref-list>
<title>References</title>
<ref id="B1">
<label>1.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Ramar</surname>
<given-names>K</given-names>
</name>
<name>
<surname>Malhotra</surname>
<given-names>RK</given-names>
</name>
<name>
<surname>Carden</surname>
<given-names>KA</given-names>
</name>
<name>
<surname>Martin</surname>
<given-names>JL</given-names>
</name>
<name>
<surname>Abbasi-Feinberg</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Aurora</surname>
<given-names>RN</given-names>
</name>
<etal/>
</person-group> <article-title>Sleep Is Essential to Health: An American Academy of Sleep Medicine Position Statement</article-title>. <source>J Clin Sleep Med</source> (<year>2021</year>) <volume>17</volume>(<issue>10</issue>):<fpage>2115</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.5664/jcsm.9476</pub-id>
<pub-id pub-id-type="pmid">34170250</pub-id>
</mixed-citation>
</ref>
<ref id="B2">
<label>2.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Zhao</surname>
<given-names>YZ</given-names>
</name>
<name>
<surname>Zhang</surname>
<given-names>WL</given-names>
</name>
<name>
<surname>Zhang</surname>
<given-names>KW</given-names>
</name>
<name>
<surname>He</surname>
<given-names>YQ</given-names>
</name>
<name>
<surname>Xue</surname>
<given-names>WQ</given-names>
</name>
<name>
<surname>Yang</surname>
<given-names>DW</given-names>
</name>
<etal/>
</person-group> <article-title>Sleep Pattern, Lifestyle Pattern, and Risks of Overall and 20 Types of Cancers: Findings From the UK Biobank Cohort</article-title>. <source>Int J Public Health</source> (<year>2025</year>) <volume>69</volume>:<fpage>1607726</fpage>. <pub-id pub-id-type="doi">10.3389/ijph.2024.1607726</pub-id>
<pub-id pub-id-type="pmid">39896234</pub-id>
</mixed-citation>
</ref>
<ref id="B3">
<label>3.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Kocevska</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Lysen</surname>
<given-names>TS</given-names>
</name>
<name>
<surname>Dotinga</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Koopman-Verhoeff</surname>
<given-names>ME</given-names>
</name>
<name>
<surname>Luijk</surname>
<given-names>MPCM</given-names>
</name>
<name>
<surname>Antypa</surname>
<given-names>N</given-names>
</name>
<etal/>
</person-group> <article-title>Sleep Characteristics Across the Lifespan in 1.1 Million People from the Netherlands, United Kingdom and United States: A Systematic Review and Meta-Analysis</article-title>. <source>Nat Hum Behav</source> (<year>2021</year>) <volume>5</volume>(<issue>1</issue>):<fpage>113</fpage>&#x2013;<lpage>22</lpage>. <pub-id pub-id-type="doi">10.1038/s41562-020-00965-x</pub-id>
<pub-id pub-id-type="pmid">33199855</pub-id>
</mixed-citation>
</ref>
<ref id="B4">
<label>4.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Morin</surname>
<given-names>CM</given-names>
</name>
<name>
<surname>Jarrin</surname>
<given-names>DC</given-names>
</name>
</person-group>. <article-title>Epidemiology of Insomnia: Prevalence, Course, Risk Factors, and Public Health Burden</article-title>. <source>Sleep Med Clin</source> (<year>2022</year>) <volume>17</volume>(<issue>2</issue>):<fpage>173</fpage>&#x2013;<lpage>91</lpage>. <pub-id pub-id-type="doi">10.1016/j.jsmc.2022.03.003</pub-id>
<pub-id pub-id-type="pmid">35659072</pub-id>
</mixed-citation>
</ref>
<ref id="B5">
<label>5.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Benjafield</surname>
<given-names>AV</given-names>
</name>
<name>
<surname>Sert Kuniyoshi</surname>
<given-names>FH</given-names>
</name>
<name>
<surname>Malhotra</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Martin</surname>
<given-names>JL</given-names>
</name>
<name>
<surname>Morin</surname>
<given-names>CM</given-names>
</name>
<name>
<surname>Maurer</surname>
<given-names>LF</given-names>
</name>
<etal/>
</person-group> <article-title>Estimation of the Global Prevalence and Burden of Insomnia: A Systematic Literature Review-Based Analysis</article-title>. <source>Sleep Med Rev</source> (<year>2025</year>) <volume>82</volume>:<fpage>102121</fpage>. <pub-id pub-id-type="doi">10.1016/j.smrv.2025.102121</pub-id>
<pub-id pub-id-type="pmid">40627924</pub-id>
</mixed-citation>
</ref>
<ref id="B6">
<label>6.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Senaratna</surname>
<given-names>CV</given-names>
</name>
<name>
<surname>Perret</surname>
<given-names>JL</given-names>
</name>
<name>
<surname>Lodge</surname>
<given-names>CJ</given-names>
</name>
<name>
<surname>Lowe</surname>
<given-names>AJ</given-names>
</name>
<name>
<surname>Campbell</surname>
<given-names>BE</given-names>
</name>
<name>
<surname>Matheson</surname>
<given-names>MC</given-names>
</name>
<etal/>
</person-group> <article-title>Prevalence of Obstructive Sleep Apnea in the General Population: A Systematic Review</article-title>. <source>Sleep Med Rev</source> (<year>2017</year>) <volume>34</volume>:<fpage>70</fpage>&#x2013;<lpage>81</lpage>. <pub-id pub-id-type="doi">10.1016/j.smrv.2016.07.002</pub-id>
<pub-id pub-id-type="pmid">27568340</pub-id>
</mixed-citation>
</ref>
<ref id="B7">
<label>7.</label>
<mixed-citation publication-type="book">
<person-group person-group-type="editor">
<name>
<surname>Mathers</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Fat</surname>
<given-names>DM</given-names>
</name>
<name>
<surname>Boerma</surname>
<given-names>JT</given-names>
</name>
</person-group>, editors. <article-title>World Health Organization</article-title>. <source>The Global Burden of Disease: 2004 Update</source>. <publisher-name>Geneva: World Health Organization</publisher-name> (<year>2008</year>).</mixed-citation>
</ref>
<ref id="B8">
<label>8.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Hay</surname>
<given-names>SI</given-names>
</name>
<name>
<surname>Ong</surname>
<given-names>KL</given-names>
</name>
<name>
<surname>Santomauro</surname>
<given-names>DF</given-names>
</name>
<name>
<surname>Aalipour</surname>
<given-names>MA</given-names>
</name>
<name>
<surname>Aalruz</surname>
<given-names>H</given-names>
</name>
<etal/>
</person-group> <article-title>Burden of 375 Diseases and Injuries, Risk-Attributable Burden of 88 Risk Factors, and Healthy Life Expectancy in 204 Countries and Territories, Including 660 Subnational Locations, 1990&#x2013;2023: A Systematic Analysis for the Global Burden of Disease Study 2023</article-title>. <source>The Lancet</source> (<year>2025</year>) <volume>406</volume>(<issue>10513</issue>):<fpage>1873</fpage>&#x2013;<lpage>922</lpage>. <pub-id pub-id-type="doi">10.1016/S0140-6736(25)01637-X</pub-id>
</mixed-citation>
</ref>
<ref id="B9">
<label>9.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Bioulac</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Micoulaud-Franchi</surname>
<given-names>JA</given-names>
</name>
<name>
<surname>Arnaud</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Sagaspe</surname>
<given-names>P</given-names>
</name>
<name>
<surname>Moore</surname>
<given-names>N</given-names>
</name>
<name>
<surname>Salvo</surname>
<given-names>F</given-names>
</name>
<etal/>
</person-group> <article-title>Risk of Motor Vehicle Accidents Related to Sleepiness at the Wheel: A Systematic Review and Meta-Analysis</article-title>. <source>Sleep</source> (<year>2017</year>) <volume>40</volume>(<issue>10</issue>). <pub-id pub-id-type="doi">10.1093/sleep/zsx134</pub-id>
<pub-id pub-id-type="pmid">28958002</pub-id>
</mixed-citation>
</ref>
<ref id="B10">
<label>10.</label>
<mixed-citation publication-type="journal">
<collab>GBD 2021 Nervous System Disorders Collaborators</collab>. <article-title>Global, Regional, and National Burden of Disorders Affecting the Nervous System, 1990&#x2013;2021: A Systematic Analysis for the Global Burden of Disease Study 2021</article-title>. <source>Lancet Neurol</source> (<year>2024</year>) <volume>23</volume>(<issue>4</issue>):<fpage>344</fpage>&#x2013;<lpage>81</lpage>. <pub-id pub-id-type="doi">10.1016/S1474-4422(24)00038-3</pub-id>
<pub-id pub-id-type="pmid">38493795</pub-id>
</mixed-citation>
</ref>
</ref-list>
<fn-group>
<fn fn-type="custom" custom-type="edited-by">
<p>
<bold>Edited by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/943079/overview">Nino Kuenzli</ext-link>, Swiss Tropical and Public Health Institute (Swiss TPH), Switzerland</p>
</fn>
</fn-group>
</back>
</article>