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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Public Health Rev</journal-id>
<journal-title>Public Health Reviews</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Public Health Rev</abbrev-journal-title>
<issn pub-type="epub">2107-6952</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">1608084</article-id>
<article-id pub-id-type="doi">10.3389/phrs.2024.1608084</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Public Health Archive</subject>
<subj-group>
<subject>Commentary</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Polio Eradication in Pakistan: Innovation and Digitalization&#x2014;the Key to Crossing the Finish Line</article-title>
<alt-title alt-title-type="left-running-head">Awan</alt-title>
<alt-title alt-title-type="right-running-head">Digitalization and Polio Eradication</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Awan</surname>
<given-names>Amna</given-names>
</name>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/2877992/overview"/>
</contrib>
</contrib-group>
<aff>
<institution>Primary and Secondary Healthcare Department, Punjab</institution>, <addr-line>Lahore</addr-line>, <country>Pakistan</country>
</aff>
<author-notes>
<fn fn-type="edited-by">
<p>
<bold>Edited by:</bold> <ext-link ext-link-type="uri" xlink:href="https://loop.frontiersin.org/people/443300/overview">Ana Ribeiro</ext-link>, University Porto, Portugal</p>
</fn>
<corresp id="c001">&#x2a;Correspondence: Amna Awan, <email>amnadoc13@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>03</day>
<month>01</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="collection">
<year>2024</year>
</pub-date>
<volume>45</volume>
<elocation-id>1608084</elocation-id>
<history>
<date date-type="received">
<day>08</day>
<month>11</month>
<year>2024</year>
</date>
<date date-type="accepted">
<day>12</day>
<month>12</month>
<year>2024</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2025 Awan.</copyright-statement>
<copyright-year>2025</copyright-year>
<copyright-holder>Awan</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. PHR is edited by the Swiss School of Public Health (SSPH&#x2b;) in a partnership with the Association of Schools of Public Health of the European Region (ASPHER)&#x2b;</p>
</license>
</permissions>
<kwd-group>
<kwd>polio eradication</kwd>
<kwd>microplanning</kwd>
<kwd>innovation framework</kwd>
<kwd>GIS mapping</kwd>
<kwd>GPS tracking of vaccinators</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<sec id="s1">
<title>Introduction</title>
<p>The global polio eradication initiative (GPEI), which started as a resolve from World Health Organization (WHO) leaders in 1988 to eradicate polio globally, has been labelled as the largest international health initiative to date. Billions of dollars and thousands of employees have been deployed worldwide since its conception, with the singular aim of eradicating this disease [<xref ref-type="bibr" rid="B1">1</xref>]. The first 14&#xa0;years of this program saw huge success as indigenous polio was eradicated in all but six countries in the world [<xref ref-type="bibr" rid="B2">2</xref>].</p>
<p>The current situation in 2024 is that polio has been eliminated in all but two countries of the world, the exceptions being Pakistan and Afghanistan. Nigeria was the latest country to achieve elimination status in 2020 [<xref ref-type="bibr" rid="B3">3</xref>].</p>
<p>This paper discusses the introduction of <bold>innovative technology</bold> to address the current gaps in Pakistan&#x2019;s polio program. <bold>Public Health Innovation Framework</bold> has been proposed in the paper as a guiding tool for the introduction of this innovation to the polio program of Pakistan.</p>
</sec>
<sec id="s2">
<title>Problem Statement</title>
<p>Pakistan has failed to achieve polio-free status despite monumental international donor support, advocacy for the program, and long-standing commitment from the country to the program. By failing to achieve polio-free status in the last decade, the country has missed an important window. This has made the achievement of future targets more difficult due to new challenges such as population explosion, climate change, economic recession and vaccine hesitancy in the post-COVID era, misinformation, social media, and increased inequality [<xref ref-type="bibr" rid="B4">4</xref>].</p>
<p>These newer challenges mean that new solutions must be introduced to tackle old problems. However, the Pakistan polio program has not been updated in many years. The supplementary immunization activities (SIAs) and polio campaigns are paper-based and outdated, and no attempt has been made to digitalize the program [<xref ref-type="bibr" rid="B4">4</xref>].</p>
<p>The PEI program in Pakistan was on track, with significant progress being made from 2015. However, the <bold>surge of cases in 2019 followed by the COVID-19 pandemic</bold> proved to be enough to derail progress. The halting of activities and transfer of polio resources to COVID-19 vaccinations resulted in an increased number of cases in 2020. The number of cases decreased in 2021, either due to relaxed surveillance or restriction of inter- and cross-border movements due to lockdowns. The current situation in Pakistan is that 40 confirmed WPV cases have been notified since 24 Oct 2024, and <bold>environmental samples</bold> are continuously positive in many urban and peri-urban areas of Pakistan [<xref ref-type="bibr" rid="B5">5</xref>]. This signifies continuous transmission of the virus in the communities, due to the presence of unvaccinated <bold>&#x201c;missed children</bold>.<bold>&#x201d;</bold> In order to achieve elimination status, the country&#x2019;s focus should be on reaching and vaccinating these missed children, who are the hidden foci of transmission. This can be achieved by <bold>improving the quality rather than the quantity of our SIAs</bold>, which is contrary to the current norm [<xref ref-type="bibr" rid="B6">6</xref>].</p>
<p>As mentioned earlier, we are in unprecedented times and are facing problems with no current known solutions; therefore, this is the <bold>best time to experiment with digital technology</bold>.</p>
</sec>
<sec id="s3">
<title>Framework for Public Health Innovation</title>
<p>The tool used to introduce our proposed innovation is the Framework for Public Health Innovation [<xref ref-type="bibr" rid="B7">7</xref>]. The innovation being proposed is the introduction of <bold>GIS mapping in the micro-planning phase and using GPS technology to track paths of vaccinators in SIAs and National Immunization Days. Nigeria</bold>, the last country to eliminate polio in 2020, has introduced this GPS/GIS technology in their NIDs [<xref ref-type="bibr" rid="B8">8</xref>].</p>
</sec>
<sec id="s4">
<title>Status Quo</title>
<p>As Pakistan has failed to achieve their elimination target, and with the impending threat of funding withdrawal, it is evident that the current elimination efforts in Pakistan are not enough and need to be supplemented by innovative methods. Thus, this climate provides an ideal playground to introduce evidence-based innovation.</p>
</sec>
<sec id="s5">
<title>Type of Innovation</title>
<sec id="s5-1">
<title>Mapping of Areas for Outreach Activity Using the Geographic Information System</title>
<p>GIS mapping has been identified as an effective strategy to identify remote and hard-to-reach areas. UNICEF and GAVI recommend GIS mapping to identify zero-dose and missed children. GIS technology would also assist in identifying chronically missed settlements and would help in concentrating efforts to these high-risk areas during the SIAs [<xref ref-type="bibr" rid="B9">9</xref>].</p>
<p>As shown in <xref ref-type="fig" rid="F1">Figure 1</xref>, maps are <bold>hand-drawn by polio teams</bold> during the microplanning phases at union council level. These maps are of <bold>low quality</bold> and do not provide information like geographical complexity or hard-to-reach areas. Thus, these maps have low utility in practice and serve no purpose other than filling a formal requirement by WHO. On the contrary, GIS maps used for immunization in Chad gave the exact location of settlements, and planners have identified the location of missed populations using this map [<xref ref-type="bibr" rid="B10">10</xref>].</p>
<fig id="F1" position="float">
<label>FIGURE 1</label>
<caption>
<p>Sample Hand drawn map used during micro-planning in Pakistan&#x2019;s Polio Program.</p>
</caption>
<graphic xlink:href="phrs-45-1608084-g001.tif"/>
</fig>
</sec>
<sec id="s5-2">
<title>GPS Tracking of Vaccinators in the Field</title>
<p>A GPS system would aid in monitoring the campaigns. A web-based tracking dashboard was developed in Nigeria that tracked the vaccinators through a GPS tracking system during campaigns; this could be simulated in Pakistan&#x2019;s polio SIAs. Such a tracking system would aid in the supervision of vaccinators as well as in identification of missed pockets [<xref ref-type="bibr" rid="B8">8</xref>].</p>
<p>The GIS/GPS tracking process can be introduced in a sequential manner.</p>
</sec>
</sec>
<sec id="s6">
<title>First Stage</title>
<p>The innovation should be piloted in high-risk districts of <bold>Sindh and Baluchistan</bold>, where most polio cases have been reported.</p>
</sec>
<sec id="s7">
<title>Second Stage</title>
<p>A nationwide SIA should be planned, targeting the <bold>high-risk mobile population (HRMP)</bold>. This would include the nomadic population who do not come under formal health systems. A <bold>targeted campaign</bold> would be launched all over the country using the results and gains achieved in the first stage.</p>
</sec>
<sec id="s8">
<title>Third Stage</title>
<p>Digitalization would be formally incorporated into the polio program.</p>
</sec>
<sec id="s9">
<title>Partnerships</title>
<p>WHO and UNICEF, being the main partners, would work in collaboration with the districts. However, the main ownership of the initiative would belong to governmental bodies. Ownership of the innovation is essential to achieve sustainable gains, as seen in polio elimination in India and Nigeria.</p>
</sec>
<sec id="s10">
<title>Accountability</title>
<p>The introduction of technology would involve the use of resources; thus, strict accountability for governmental agencies should be introduced to the program. <bold>Independent third parties with no conflict of interest</bold> should be involved in the accountability process [<xref ref-type="bibr" rid="B8">8</xref>].</p>
<sec id="s10-1">
<title>Conclusion</title>
<p>The presence of missed and zero-dose children is a major barrier to polio eradication. Weak routine immunization in the country is a gap that can be filled through operational innovation in NIDs.</p>
<p>There is a good system of polio teams with predefined roles at union council levels in the country. The teams have experience in using apps for data entry from previous pilot projects and in their routine jobs as well. Thus, the introduction of the innovation recommended in this report seems feasible in the current circumstances. Digitalization is the last step Pakistan&#x2019;s polio initiative needs to take in order to cross the finish line.</p>
</sec>
</sec>
</body>
<back>
<sec sec-type="author-contributions" id="s11">
<title>Author Contributions</title>
<p>The author confirms being the sole contributor of this work and has approved it for publication.</p>
</sec>
<sec sec-type="funding-information" id="s12">
<title>Funding</title>
<p>The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.</p>
</sec>
<sec sec-type="COI-statement" id="s13">
<title>Conflict of Interest</title>
<p>The author declares that they do not have any conflicts of interest.</p>
</sec>
<sec sec-type="ai-statement" id="s14">
<title>Generative AI Statement</title>
<p>The author(s) declare that no Generative AI was used in the creation of this manuscript.</p>
</sec>
<ref-list>
<title>References</title>
<ref id="B1">
<label>1.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Aylward</surname>
<given-names>RB</given-names>
</name>
<name>
<surname>Maher</surname>
<given-names>C</given-names>
</name>
</person-group>. <article-title>Interrupting Poliovirus Transmission - New Solutions to an Old Problem</article-title>. <source>Biol Sci</source> (<year>2006</year>) <volume>34</volume>:<fpage>133</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1016/j.biologicals.2006.02.012</pub-id>
</citation>
</ref>
<ref id="B2">
<label>2.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Thompson</surname>
<given-names>KM</given-names>
</name>
<name>
<surname>Kalkowska</surname>
<given-names>DA</given-names>
</name>
</person-group>. <article-title>An Updated Economic Analysis of the Global Polio Eradication Initiative</article-title>. <source>Risk Anal</source> (<year>2021</year>) <volume>41</volume>(<issue>2</issue>):<fpage>393</fpage>&#x2013;<lpage>406</lpage>. <pub-id pub-id-type="doi">10.1111/risa.13665</pub-id>
</citation>
</ref>
<ref id="B3">
<label>3.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Afzal</surname>
<given-names>N</given-names>
</name>
<name>
<surname>Firdous</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Asmat</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Missen</surname>
<given-names>MMS</given-names>
</name>
<name>
<surname>Akhtar</surname>
<given-names>N</given-names>
</name>
<name>
<surname>Ullah</surname>
<given-names>S</given-names>
</name>
<etal/>
</person-group> <article-title>Mobile Technology Based Polio Vaccination System (PVS)- First Step Towards Polio-Free Pakistan</article-title>. <source>IJACSA</source> (<year>2017</year>) <volume>8</volume>(<issue>2</issue>):<fpage>415</fpage>&#x2013;<lpage>29</lpage>. <pub-id pub-id-type="doi">10.14569/ijacsa.2017.080253</pub-id>
</citation>
</ref>
<ref id="B4">
<label>4.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Ataullahjan</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Ahsan</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Soofi</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Habib</surname>
<given-names>MA</given-names>
</name>
<name>
<surname>Bhutta</surname>
<given-names>ZA</given-names>
</name>
</person-group>. <article-title>Eradicating Polio in Pakistan: A Systematic Review of Programs and Policies</article-title>. <source>Expert Rev Vaccin</source> (<year>2021</year>) <volume>20</volume>(<issue>6</issue>):<fpage>661</fpage>&#x2013;<lpage>78</lpage>. <pub-id pub-id-type="doi">10.1080/14760584.2021.1915139</pub-id>
</citation>
</ref>
<ref id="B5">
<label>5.</label>
<citation citation-type="book">
<collab>Polio Cases in provinces</collab>. <source>Islamabad. Pakistan Polio Eradication Initiative</source> (<year>2024</year>). <comment>Available from: <ext-link ext-link-type="uri" xlink:href="https://www.endpolio.com.pk/polioin-pakistan/polio-cases-in-provinces">https://www.endpolio.com.pk/polioin-pakistan/polio-cases-in-provinces</ext-link> (Accessed October 24, 2024)</comment>.</citation>
</ref>
<ref id="B6">
<label>6.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Larson</surname>
<given-names>HJ</given-names>
</name>
<name>
<surname>Paterson</surname>
<given-names>P</given-names>
</name>
</person-group>. <article-title>Eradicating Polio: Persisting Challenges beyond Endemic Countries</article-title>. <source>Expert Rev Vaccin</source> (<year>2011</year>) <volume>10</volume>(<issue>12</issue>):<fpage>1635</fpage>&#x2013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1586/erv.11.156</pub-id>
</citation>
</ref>
<ref id="B7">
<label>7.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Garney</surname>
<given-names>WR</given-names>
</name>
<name>
<surname>Wilson</surname>
<given-names>KL</given-names>
</name>
<name>
<surname>Garcia</surname>
<given-names>KM</given-names>
</name>
<name>
<surname>Muraleetharan</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Esquivel</surname>
<given-names>CH</given-names>
</name>
<name>
<surname>Spadine</surname>
<given-names>MN</given-names>
</name>
<etal/>
</person-group> <article-title>Supporting and Enabling the Process of Innovation in Public Health: The Framework for Public Health Innovation</article-title>. <source>Int J Environ Res Public Health</source> (<year>2022</year>) <volume>19</volume>:<fpage>10099</fpage>. <pub-id pub-id-type="doi">10.3390/ijerph191610099</pub-id>
</citation>
</ref>
<ref id="B8">
<label>8.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Barau</surname>
<given-names>I</given-names>
</name>
<name>
<surname>Zubairu</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Mwanza</surname>
<given-names>MN</given-names>
</name>
<name>
<surname>Seaman</surname>
<given-names>VY</given-names>
</name>
</person-group>. <article-title>Improving Polio Vaccination Coverage in Nigeria through the Use of Geographic Information System Technology</article-title>. <source>JID</source> (<year>2014</year>) <volume>210</volume>(<issue>Suppl. 1</issue>):<fpage>S102</fpage>&#x2013;<lpage>S110</lpage>. <pub-id pub-id-type="doi">10.1093/infdis/jiu010</pub-id>
</citation>
</ref>
<ref id="B9">
<label>9.</label>
<citation citation-type="journal">
<article-title>The Use of Digital Technologies and Approaches for Real-Time Monitoring of Supplementary Immunization Activities. Good Practices and Lessons Learned</article-title>. <source>New York: United Nation&#x2019;s Children&#x2019;s FUND (UNICEF)</source> (<year>2021</year>) <comment>Available from: <ext-link ext-link-type="uri" xlink:href="https://www.unicef.org/media/93781/file/gavi-unicef-digital-technology-immunization-2021.pdf">https://www.unicef.org/media/93781/file/gavi-unicef-digital-technology-immunization-2021.pdf</ext-link>. (Accessed</comment>: <comment>October 24, 2024)</comment>.</citation>
</ref>
<ref id="B10">
<label>10.</label>
<citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname>Ajiri</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Okeibunor</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Aiyeoribe</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Ntezayabo</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Mailhot</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Nzioki</surname>
<given-names>M</given-names>
</name>
<etal/>
</person-group> <article-title>Response to Poliovirus Outbreaks in the Lake Chad Sub-region: A GIS Mapping Approach</article-title>. <source>J Immunological Sci</source> (<year>2021</year>) <volume>S</volume>(<issue>002</issue>):<fpage>93</fpage>&#x2013;<lpage>100</lpage>. <pub-id pub-id-type="doi">10.29245/2578-3009/2021/S2.1115</pub-id>
</citation>
</ref>
</ref-list>
</back>
</article>